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Would you apply the strategy/science/culture framework differently at the 0-to-1 stage, vs at a later, more established stage? Anything come to mind immediately?

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To carry question 3 a bit further: given that a product strategy is wrong +/- 50% of the time, how can you ensure you're at a company where that sort of failure is permissible, expected, and, ideally, welcomed in these high-stakes decisions?

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